Longevity & Aging Research Peptides
FOXO4-DRI
FOX04-DRI (Retro-Inverso) is a synthetic, slightly modified version of the standard FOXO4 protein. The modification prolongs half-life of the protein and allows it to interfere with normal FOXO4 function. FOXO4-DRI has been shown in research to prevent normal FOXO4 binding to p53, thereby allowing for elimination of senescent cells, improved organ function, and younger tissue “biological age.” FOXO4-DRI impacts insulin signaling, cell cycle regulation, and oxidative stress signaling pathways. FOXO4-DRI is a cell penetrating peptide shown to selectively induce apoptosis of senescent cells thereby reversing effects of aging in animal studies.
Overview
Full product description will be added soon.
Technical Specifications
- Molecular Formula
- C₂₂₈H₃₈₈N₈₆O₆₄
- Molecular Weight
- 5358.05 g/mol
- Purity
- 99% HPLC
- Length
- 46 aa
- CAS Number
- —
- Research Area
- Cellular senescence, senolysis (clearance of senescent cells), and the FOXO4-p53 protein interaction.
Molecular Information
- Molecular Formula
- C₂₂₈H₃₈₈N₈₆O₆₄
- Molecular Weight
- 5358.05 g/mol
- CAS Number
- —
- Sequence Length
- 46 aa
Research Information
Cellular senescence, senolysis (clearance of senescent cells), and the FOXO4-p53 protein interaction.
This product is supplied for research and informational purposes only. Please review applicable regulations in your jurisdiction before use.
Storage Information
- Storage
- Store lyophilized at -20°C; protect from light and moisture. Reconstitute with bacteriostatic water; store reconstituted material refrigerated and use per laboratory procedure.
- Appearance
- Lyophilized powder
- Solubility
- Soluble in bacteriostatic water; please refer to the product COA for specific solvent recommendations.
Documentation
Documentation is available on request. Request COA / specification sheet
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