AOD-9604

NAD+

Nicotinamide Adenine Dinucleotide

NAD+ (nicotinamide adenine dinucleotide) is a vital coenzyme in all living cells, essential for metabolic processes and cellular function. It acts as a mediator of redox reactions, alternating between its oxidized (NAD+) and reduced (NADH) forms to facilitate electron transfer, crucial for energy production and sustaining life. Involved in over 500 enzymatic reactions, NAD+ is central to maintaining cellular homeostasis. Research shows that NAD+ may be beneficial in improving muscle function, protecting cells of the nervous system, and generally reducing the effects of aging. Beyond energy metabolism, NAD+ supports DNA repair and gene regulation through enzymes like sirtuins and PARPs. Sirtuins use NAD+ to regulate cellular functions such as DNA repair, gene expression, and aging, while PARPs utilize it to repair DNA damage and maintain genomic stability. These roles underscore NAD+'s importance in cellular integrity and combating aging.

Formula

C₂₁H₂₇N₇O₁₄P₂

MW

663.43 g/mol

Purity

99% HPLC

Length

—

Cellular energy metabolism, mitochondrial function, redox reactions, and cellular senescence.

MOTS-c

MOTS-c is a mitochondrial-derived peptide (MDP) composed of 16 amino acids, which plays a critical role in cellular metabolic regulation. Synthesized within mitochondria, MOTS-c functions by modulating the cellular energy balance through pathways involved in glucose metabolism, insulin sensitivity, and cellular stress response. MOTS-c exerts its effects by translocating to the nucleus, where it influences the expression of genes related to mitochondrial biogenesis and metabolic regulation, particularly under conditions of metabolic stress. Research has shown this peptide to improve exercise capacity, reduce obesity, insulin resistance and other disease processes such as osteoporosis and the mitigation of metabolic disorders and age-associated diseases.

Formula

C₁₀₁H₁₅₂N₂₈O₂₂S₂

MW

2174.64 g/mol

Purity

99% HPLC

Length

16 aa

Mitochondrial function, energy metabolism, glucose metabolism, insulin sensitivity, and cellular stress responses.

Kisspeptin-10

Kisspeptin acts to control hormone secretion as it relates to reproduction. Kisspeptin has been shown to influence testosterone levels and sex-related behaviors like drive and motivation. Research also suggests it may help to reverse some of the effects of aging.

Formula

C₆₃H₈₃N₁₇O₁₄

MW

1302.40 g/mol

Purity

99% HPLC

Length

10 aa

Research on reproductive endocrine regulation, GnRH (gonadotropin-releasing hormone) secretion, and signaling within the reproductive axis.

IGF-1 LR3

Long R3 Insulin-like Growth Factor-1

IGF-1 LR3 Receptor Grade is a premium research reagent for use in cell growth studies, IGF receptors and IGF binding proteins and is more potent than rH IGF1 and media grade IGF1. (Standard IGF1-LR3.)

Formula

C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉

MW

9117.50 g/mol

Purity

99% HPLC

Length

83 aa

IGF-1 receptor signaling, cell growth, cell differentiation, and metabolic regulation.