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Metabolic Research Peptides

5-Amino-1MQ

5-amino-1MQ is a small molecule that blocks the activity of the enzyme called nicotinamide N-methyltransferase (NNMT). NNMT is a very important component in metabolism and energy and is predominantly active in fat tissue. By blocking NNMT, 5-amino-1MQ stimulates an increase in nicotinamide adenine dinucleotide (NAD+), a cofactor that is central to cellular metabolism, thereby increasing metabolic rate and activating a gene called sirtuin-1 (SIRT1). SIRT1 is also known as the "longevity gene" because of its role in reducing the risk of diabetes, obesity, metabolic syndrome, atherosclerosis and other forms of cardiovascular disease, kidney disease, liver disease, neurodegeneration, and cancer. Research in mice given 5-amino-1MQ showed a 7% reduction in body mass over 10 days without any changes in food intake, compared to controls. Research has shown that decreasing NNMT may help shrink fat cells and reduce the size of fat deposits.

C₁₀H₁₁N₂159.21 g/mol

Overview

5-Amino-1-methylquinolinium

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Technical Specifications

Molecular Formula
C₁₀H₁₁N₂
Molecular Weight
159.21 g/mol
Purity
99% HPLC
Length
—
CAS Number
42464-96-0
Research Area
5-amino-1MQ is a small molecule capable of blocking the activity of nicotinamide N-methyltransferase (NNMT).

Molecular Information

Molecular Formula
C₁₀H₁₁N₂
Molecular Weight
159.21 g/mol
CAS Number
42464-96-0
Sequence Length
—

Research Information

5-amino-1MQ is a small molecule capable of blocking the activity of nicotinamide N-methyltransferase (NNMT).

This product is supplied for research and informational purposes only. Please review applicable regulations in your jurisdiction before use.

Storage Information

Storage
Store lyophilized at -20°C; protect from light and moisture. Reconstitute with bacteriostatic water; store reconstituted material refrigerated and use per laboratory procedure.
Solubility
Soluble in bacteriostatic water; please refer to the product COA for specific solvent recommendations.

Documentation

Documentation is available on request. Request COA / specification sheet

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