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Industry & Quality

Understanding Purity: HPLC, Sequence Analysis, and Identity Verification

Published September 4, 2026 Updated September 4, 2026 PeptideLab Quality Office

Analytical Methods Used for Research Peptides

  • HPLC: separates components by hydrophobicity to determine percent purity.
  • Mass spectrometry (MS): confirms molecular weight and sequence identity.
  • Amino acid analysis: verifies composition ratios.

Reading a Certificate of Analysis

A COA should include batch number, product name and sequence, the measured purity with the method used, mass spectrometry results, storage instructions, and the date of analysis.

ItemTypical Entry
Purity (HPLC)≥ 98%
Mass spectrometryObserved m/z matches theoretical
FormLyophilized powder
Industry & QualityMore in Industry & Quality

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